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  • The British Society for Rheumatology guideline for the management of gout
    Rheumatology (Oxford). 2017;56(7):e1-e20

    Bottom Line

    This guideline provides clear recommendations and pays attention to implementation and audit issues. The guideline group had a good representation of different expertise. However, lacking details about the evidence review methods lets it down.
  • Evidence-based recommendations for antibiotic usage to treat endodontic infections and pain: a systematic review of randomized controlled trials
    J Am Dent Assoc. 2016;147(3):186-91

    Bottom Line

    Limited evidence did not indicate the need to prescribe antibiotics to prevent endodontic infection or pain. Only articles published in English were included, which meant that some eligible studies may have been excluded. A limited number of databases were searched to identify the relevant literature, which seemed to be inappropriate. Only search terms were provided, hence in the absence of a complete search strategy, it was not possible to confirm if all relevant studies were included in this review. No information was reported regarding the number of authors involved in the data extraction and quality assessment process, which meant bias of the included studies may not be overruled. Further randomised controlled clinical trials with large study populations were required to assess the need for prescribing antibiotics for endodontic infection or pain.

    Risk of Bias Assessment

    Only articles published in English were included, which meant that some eligible studies may have been excluded. MEDLINE, Scopus, Cochrane Library and ClinicalTrials.gov were searched to identify the relevant literature. Only search terms were provided, hence in the absence of a complete search strategy, it was not possible to confirm if all relevant studies were included in this review. No information was reported regarding the number of authors involved in the data extraction and quality assessment process.
  • Transforaminal epidural steroid injections for treating lumbosacral radicular pain from herniated intervertebral discs: a systematic review and meta-analysis
    Anesth Analg. 2016;122(3):857-70

    Bottom Line

    The current evidence suggested that transforaminal epidural steroid injections provided mild analgesic benefit at three months in patients with lumbosacral radicular pain secondary to herniated intervertebral discs. A restriction to published data in English meant that some eligible studies may have been excluded. No information was provided regarding the number of reviewers involved in the selection of studies and data extraction process, hence reviewer error and bias could not be ruled out. Further high-quality studies were required to evaluate appropriate dosages, adverse effects, the number of procedures, and the effect of this intervention on psychological disability and quality of life.

    Risk of Bias Assessment

    The searches were restricted to articles published in English. No information had been provided regarding the number of reviewers involved in the selection of studies and data extraction process.
  • Effects of intravenous and oral magnesium on reducing migraine: a meta-analysis of randomized controlled trials
    Pain Physician. 2016;19(1):E97-E112

    Bottom Line

    The evidence suggested that intravenous magnesium was beneficial for reducing acute migraine attacks and oral magnesium supplements alleviated the frequency and intensity of migraine attacks. Intravenous and oral magnesium could be considered as adjunctive therapies for the controlling and prophylaxis of migraines. Only English and Chinese language studies were included, so some relevant studies may have been missed, in addition the full search strategy was not reported. More randomised controlled trials were needed to examine the effects of intravenous magnesium on acute migraine attacks and oral magnesium on migraine prophylaxis.

    Risk of Bias Assessment

    Only English and Chinese language studies were included, so some relevant studies may have been missed, in addition the full search strategy was not reported.
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